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pentobarbital will minimize the level or effect of gefitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism.Keep track of Carefully (1)pentobarbital will lower the level or impact of benzhydrocodone/acetaminophen by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Intently. Warning when discontinuing CYP3A4 in